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ADVERSE REACTIONS IDENTIFIED
ASPARTAME RESEARCH STUDIES
( Non-Industry Sponsored or Funded )

DATE
#		 Researcher/Research Findings/Publication Adverse Reaction Identified Funding Source
1994
#81		 Gerrad JW, Richardson JS, Donat J, et. al.
Neuropharmacological Evaltuation of Movement Disorders that are Adverse Reactions to Specific Foods Including Aspartame. International Journal of Neurosciences 1994 May;76(1-2):61-69.		 Adverse
Reaction
Identified		 University of Saskatchewan, Canada
1995
#82		 Barua J, Bal A,
A Health Alert: Emerging Facts About Aspartame
Journal Diabetes Associations India, 1995;35(4):92-107		 Adverse
Reaction
Identified		 S.L. Raheja Hospital, Bombay India
1995
#83		 Sonnewald U, Muller T, Unsgaro G, Peterson SB,
et. al.
Effects of Asparate on 45 CA Influx and LDH Leakage from Nerve Cells in Culture
Neuroreport 1995 45 CA;6(2):318-320		 Adverse
Reaction
Identified		 Research Council of Norway
1995
#84		 Kulczychui A Jr.
Aspartame Induced Hives
Journal of Allergy and Clinical Immunology 1995;95(2):630-640		 Adverse
Reaction
Identified		 Washington University
1996
#85		 Roberts HJ, Aspartame as a Cause of Allgeric Reactions, Including Anaphylaxis
Acrh Internal Medicine 1996;156(9);1027-1028		 Adverse
Reaction
Identified		 Palm Beach Insitute for Medical Research
1996
#86		 Olney JW, Farber NB, Spitznagel E, Robins L.
Increasing Brain Tumor Rates:
Is There A Link to Aspartame?
Journal of Neuropathylogy and Experimental Nuerology 1996;55(11);1115-1123.		 Adverse
Reaction
Identified		 National Institutes
Mental Health
1998
#87		 Trocho C, Pardo R, Rafecas I, Virgili J, Remesar A, Fernandez-Lopez JA, Alemany M.
Formaldehyde Derived from Dietary Aspartame Binds to Tissues Compoents in Vitro
Life Sciences 1998;63(5);337-349		 Adverse
Reaction
Identified		 University of Barcelona Spain
2000
#88		 Carpal Tunnel Syndrome Due to Aspartame Disease
Roberts, HJ, MD, FACP
Staff St. Mary's Hospital-West Palm Beach
Townsend Letter for Doctors & Patients, Nov. 2000, pp 82-84 		Adverse
Reaction
Identified		 St.Mary's Hospital
West Palm Beach, FL
1980
#89		 Study E33-34 in Master File 134 On Aspartame
On File at the FDA Hearing Clerk's Office 		Adverse
Reaction
Identified		 Submitted to FDA

The following is what the FDA has been conducting regarding Aspartame since 1986, mainly monitoring the reporting of adverse reactions to Aspartame from the public and or doctors. Even though the FDA received over 10,000 reports of adverse reactions in isn't it amazing how the FDA can still state," The Safety of Aspartame Is Still Supported by the FDA?" Mind you, five of these are actual, the other two are just monitoring programs to monitor reported adverse reactions to Aspartame. However, the nearly 70 other research studies listed above say there is a serious health hazard to Aspartame compared to the other five that support Aspartame. Hello...what's wrong with this picture may I ask? Am I missing something here or did someone, somewhere, especially at the FDA "FLEW OVER THE COOCOO NEST". Are they blind?

1988
#1		 Tollefson L.,
Monitoring Adverse Reactions to Food Additives in the U.S. Food and Drug Administration Regulatory Toxicologoy and Pharmacology 1988;8(4):438-446		 Safety of Aspartame Supported FDA
1988
#2		 Tollefson L.
Monitoring of Adverse Reactions to Aspartame Reproted to the U.S.. Food and Drug Administration. In: Wurtman and Ritter-Walker (eds.) Dietery Phenylalanine and Brain Function. Boston: Birkhasuer, 1988 pp. 317-326		 Safety of Aspartame Supported FDA
1988
#3		 Yoast DA,
Clinical Safety of Aspartame (review).
AFP 1989, Feb:39(2):201-206.		 Safety of Aspartame Supported University of Arizona
1991
#4		 Tilson HA, Hong JS, Sobotka TS, et. al.
High Doses of Aspartame Have no Effect on Sensorimotor Function or Leaning and Memory in Rats
Neurotoxicology & Tetraology 1991;13(1):27-35.		 Safety of Aspartame Supported FDA
1992
#5		 Tollesfson L and Barnared RJ
An Analysis of FDA Passive Surveillance Reports of Seizures Associated with Consumption of Aspartame
Journal of the American Dietetic Association 1992:(5):598-601.		 Safety of Aspartame Supported FDA
1993
#6		 Tollesfson L
Multiple Chemical Sensitivity: Controlled Scientific Studies as Proof of Causation
Regulatory Toxicology and Pharmacology 1993;18:32-43		 Safety of Aspartame Supported FDA
1994
#7		 Stokes AF, Belger A, Banich MT, Bernadine E et. al.
Effects of Alcohol and Chronic Aspartame Ingestion Upon Performance in Aviation Relevant Cognitive Tasks. Aviation, Space and Environmental Medicine 1994;65:7-15.		 Safety of Aspartame Supported FDA

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Updated Sete,ber 7th, 2001
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